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ClinicalTrials.gov Updated with More Changes to Improve Usability!

Posted by on September 25th, 2017 Posted in: Consumer Health, NLM Products, Public Health

Today the National Library of Medicine (NLM) released updates to ClinicalTrials.gov as the next phase in an ongoing effort to enhance the functionality of the database. For a review of this project, visit ClinicalTrials.gov: First in a Series of Changes to Improve Usability for Stakeholders. Following are highlights of key features in the latest release. These changes were informed by user research with end-users representing various stakeholder groups as part of a continuing partnership between NLM and 18F, a federal government digital services consultancy. Additional changes to ClinicalTrials.gov are planned and information about these changes will be provided in future NLM Technical Bulletin notices.

ClinicalTrials.gov is an NLM-maintained resource that provides patients and their families, healthcare professionals, researchers, and members of the public with information about clinical studies and expanded access to investigational drugs (or “compassionate use”). Information listed on ClinicalTrials.gov is provided and updated by the study sponsor or investigator. Listing does not reflect endorsement by the National Institutes of Health. Currently, ClinicalTrials.gov contains information on 255,000 studies and expanded access across the United States and around the world.

ClinicalTrials.gov homepage
Redesigned ClinicalTrials.gov homepage

Updated Homepage and Disclaimer Text

The homepage has been simplified. Modified text containing important messages for users, including that listing of a study on ClinicalTrials.gov does not mean the study has been reviewed by the U.S. Federal Government, is displayed on the homepage and at the top of each study record page.

Enhanced Search Results Page

New features on the Search Results page are intended to provide users with additional feedback on what was searched and help users discover study records of interest more quickly. Study records first made available on ClinicalTrials.gov (or “posted”) during the past 30 days are identified by the “New” icon in the “Status” column on the List tab. Synonyms of terms used by the search engine are summarized at the top, and both search terms and synonyms appearing on the Search Results page are highlighted. Up to three entries can be displayed as a bulleted list in a column; the number of any additional entries is indicated in a fourth bullet. The “Locations” column for displaying study facility information is a new option in the “Show/Hide Columns” panel on the Search Results page.

Changes to Record Date Fields

The Last Updated field was renamed to “Last Update Submitted” and a new field titled “Last Update Posted” is now available. “Last Updated” was defined as the most recent date on which changes to a study record were submitted to ClinicalTrials.gov. That is, the date on which the most recent updates to a study record were made by the study sponsor or investigator and provided to ClinicalTrials.gov. However, delays sometimes occur between the “Last Updated” date (submitted date) and the date on which that updated study information is first accessible on ClinicalTrials.gov. The new Last Update Posted field is defined as the most recent date on which changes to a study record were posted on ClinicalTrials.gov; when updated study information is publicly available. The Last Update Posted field is displayed on ClinicalTrials.gov study records and appears in the following key features:

  • Advanced Search” for creating a focused query using any number of search fields, including “Last Update Posted”
  • Subscribe to RSS” on the Search Results page under the List tab for creating an RSS feed for a specific search to receive study records that were first added or for which updates were posted in the last 14 days
  • Show/Hide Columns” on the Search Results page under the List tab for choosing which study characteristics, including “Last Updated Posted,” to display for retrieved study records

Note: Saved searches and RSS feeds created before September 25, 2017, will continue to function, but will use the new Last Update Posted field rather than “Last Updated” (now named “Last Update Submitted”). As explained previously, this change may affect the results of a saved search and RSS feed because delays sometimes occur between the time study information is submitted to ClinicalTrials.gov and when it is available to the public.

The “First Received” and “Results First Received” date fields have been renamed “First Submitted” and “Results First Submitted,” respectively. Their definitions remain the same. The name changes are intended to clarify that these dates indicate when study information was first submitted to ClinicalTrials.gov, not when it was first “posted.”

Coming Soon to ClinicalTrials.gov

Additional enhancements to ClinicalTrials.gov are still under development and include, but are not limited to:

  • Searching for U.S. studies by city and radius in miles
  • Tools for more easily accessing Glossary content
  • Updating the study record layout to make the most relevant information more prominent

Comments, questions, and suggestions are welcome! To contact NLM, click on “Customer Support” in the footer of the ClinicalTrials.gov web site, which will take you to the NLM Customer Support page. Then click on Contact NLM at the top of the NLM Customer Support page.

Image of the author ABOUT Alan Carr
Alan Carr is the Associate Director, National Network of Libraries of Medicine, Pacific Southwest Region, based at UCLA.

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This project is funded by the National Library of Medicine, National Institutes of Health, Department of Health and Human Services, under Cooperative Agreement Number UG4LM012341 with the UCLA Louise M. Darling Biomedical Library.

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