As of December 15, PubMed/MEDLINE citations (including the backlog of citations indexed since November 19 with 2015 MeSH), the MeSH database, and the NLM Catalog were updated to reflect 2015 MeSH. The MeSH translation tables were also updated on December 15. Now that end-of-year activities are complete, MEDLINE/PubMed may be searched using 2015 MeSH vocabulary. Highlights of MEDLINE Data Changes for 2015 were previously published in the NN/LM PSR Latitudes blog. On December 16, NLM resumed daily MEDLINE updates to PubMed.