Registration is available for the 2017 Annual Conference of the Friends of the National Library of Medicine, Consequential and Reproducible Clinical Research: Charting the Course for Continuous Improvement, to be held June 14-15 at NLM’s Lister Hill National Center for Biomedical Communications Building. The conference will discuss prevention of non-repeatable research and inconsequential studies, highlight positive strategies to achieve trustworthy results and significant quality improvement in clinical research studies. The constructive and practical messages should benefit producers as well as users of clinical research discoveries. The meeting is co-sponsored by the National Library of Medicine and Research!America. The early-bird discount registration deadline is April 30. Additional information will be provided soon for recommended travel, accommodations, and the conference program.